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This matters because it demonstrates that GLP-1 medications can address both the weight retention and the metabolic dysfunction that gestational diabetes leaves behind, potentially interrupting the progression to type 2 diabetes before it starts

doi: 10.1093/nar/29.16.3433 44 JiangP

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Eluting peptides were delivered to a G2-Si HDMS mass spectrometer with ion mobility separation (Waters), ionised by electrospray ionisation (250 C capillary temperature, 3.0 kV spray voltage) and mass spectra acquired in positive ion mode over a range of 50 to 2000 m/z in enhanced high definition MS (HDMSE) or high definition MS (HDMS) mode for non-deuterated and deuterated samples, respectively

On the other, it presents a formidable challenge for maintaining steady-state concentrations